Dipartimento cardiovascolare, azienda ospedialiero universitaria ospedali riuniti, trieste. Both postmortem interval and cardiac tissue of burned corpse had a statistically significant effect where the greatest amount of protein breakdown was observed within the first 41. The recent development of a highsensitive cardiac troponin t hsctnt assay permits detection. Increased levels of cardiac troponin t appears in the blood within 3. Cardiac troponin is the preferred biomarker for the diagnosis of acute myocardial infarction ami. Blood troponin levels may be used as a diagnostic marker for stroke, although the sensitivity of this measurement is low. Troponin i is a subunit of the troponin complex tn, which is a heteromeric protein that is bound to the thin filament. Measurements of cardiacspecific troponins i and t are. Timedependent degradation pattern of cardiac troponin t. Coronary hemodynamics and myocardial metabolism of lactate, free fatty acids. Assays that are based on highaffinity antibodies and are specific for cardiac troponin t ctnt and cardiac troponin i. The cardiac troponin t ctnt is important specific biomarker in establishing diagnosis and. The data show a distinct timedependent profile corresponding to the degradation of ctnt by proteases found in cardiac muscle.
The prog nostic value of cardiac troponin t is most important as it is not dependent on age, sex, ecg changes as well as levels of age old biochemical markers such as ckmb. Cardiac troponin t levels in heart blood as a marker to. Valori elevatissimi di troponina t, rilevabili semplicemente effettuando le normali analisi del sangue, stanno ad indicare delle forti sofferenze cardiache. Scribd is the worlds largest social reading and publishing site.
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